In brief
Prince Frederik of Luxembourg, who fought a courageous battle against POLG disorder, has passed away at the young age of 22. The genetic disease, stemming from a mutation in the POLG gene, affects how cells produce energy and can severely impair multiple organ systems. Born in France and raised in Switzerland, Frederik became known for his work with the POLG Foundation, which he helped establish to promote awareness and research for the condition he himself endured. Following his diagnosis at age 14, he committed his life to supporting others with POLG and contributed a wealth of knowledge through creative initiatives, including a clothing line and a film. His father, Prince Robert, shared a touching reflection of Frederik's last days and his enduring spirit, even as he faced deterioration from pneumonia and infections.
